| Neuroprotective activity of galloylated cyanogenic glucosides and hydrolysable tannins isolated from leaves of Phyllagathis rotundifolia. | |
| | |
MedLine Citation:
|
PMID: 22093753 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The galloylated cyanogenic glucosides based on prunasin (1-7), gallotannins (8-14), ellagitannins (15-17), ellagic acid derivatives (18, 19) and gallic acid (20) isolated from the leaves of Phyllagathis rotundifolia (Melastomataceae) were investigated for their neuroprotective activity against hydrogen peroxide (H(2)O(2))-induced oxidative damage in NG108-15 hybridoma cell line. Among these compounds, the gallotannins and ellagitannins exhibited remarkable neuroprotective activities against oxidative damage in vitro as compared to galloylated cyanogenic glucosides and ellagic acid derivatives in a dose-dependent manner. They could be explored further as potential natural neuroprotectors in various remedies of neurodegenerative diseases. |
| | |
Authors:
|
Hooi Poay Tan; Daniel Zin Hua Wong; Sui Kiong Ling; Cheng Hock Chuah |
Related Documents
:
|
11312873 - Comparison of volatiles, phenolics, sugars, antioxidant vitamins, and sensory quality o... 21620863 - Helix-helix interfaces and ligand binding. 21859373 - Rapid access to ketones related to oleanolic and ursolic acids. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-7 |
Journal Detail:
|
Title: Fitoterapia Volume: - ISSN: 1873-6971 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 16930290R Medline TA: Fitoterapia Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011. Published by Elsevier B.V. |
Affiliation:
|
Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia; Phytochemistry Program, Natural Products Division, Forest Research Institute Malaysia, 52109, Kepong, Selangor, Malaysia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Formation and characterization of pDNA-loaded alginate microspheres for oral administration in mice.
Next Document: Rapid in vivo analysis of synthetic promoters for plant pathogen phytosensing.