| Neurophysiologic findings in early acute inflammatory demyelinating polyradiculoneuropathy. | |
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MedLine Citation:
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PMID: 15351375 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients with early acute inflammatory demyelinating polyradiculoneuropathy (AIDP) may not meet the current neurophysiologic criteria. OBJECTIVE: To document neurophysiologic findings in early AIDP. METHODS: Clinical and neurophysiologic data from 38 AIDP patients, assessed within 10 days of symptom onset were reviewed. RESULTS: In addition to absent H reflexes and abnormal F-wave responses in the acute stage of AIDP, abnormalities of blink reflexes, upper limb sensory responses abnormalities with spared sural responses, presence of distal CMAP dispersion, and A-waves were frequently observed. Established demyelinating neurophysiologic parameters were infrequently seen. CONCLUSIONS: Abnormalities of H reflexes and F responses were most frequently noted in early AIDP. Additionally, distal temporal dispersion, prolonged or absent blink reflexes, and A-waves were often present in the acute stage of AIDP when classic diagnostic criteria of AIDP were not satisfied. SIGNIFICANCE: Neurophysiologic studies in early AIDP frequently reveal abnormalities that are not specific of primary demyelinating neuropathy. |
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Authors:
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Steve Vucic; Kevin D Cairns; Kristin R Black; Peter Siao Tick Chong; Didier Cros |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Volume: 115 ISSN: 1388-2457 ISO Abbreviation: Clin Neurophysiol Publication Date: 2004 Oct |
Date Detail:
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Created Date: 2004-09-07 Completed Date: 2004-10-26 Revised Date: 2008-09-10 |
Medline Journal Info:
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Nlm Unique ID: 100883319 Medline TA: Clin Neurophysiol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 2329-35 Citation Subset: IM |
Affiliation:
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Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Blinking / physiology Child Child, Preschool Disease Progression Electric Stimulation Electromyography Evoked Potentials / physiology Female Guillain-Barre Syndrome / physiopathology* H-Reflex / physiology Humans Male Middle Aged Neural Conduction Neurologic Examination Retrospective Studies |
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