Document Detail

Neuropeptide Y gene expression around meal time in the Brazilian flounder Paralichthys orbignyanus.
MedLine Citation:
PMID:  22581328     Owner:  NLM     Status:  In-Data-Review    
Neuropeptide Y (NPY) is considered the major stimulant for food intake in mammals and fish. Previous results indicate that NPY is involved in the feeding behaviour of the Brazilian flounder, Paralichthys orbignyanus. In this study, we evaluated hypothalamic NPY expression before (-2 h), during (0 h) and after feeding (+2 h) in two independent experiments: (1) during a normal feeding schedule and (2) in fish fasted for 2 weeks. During normal feeding, changes in the levels of NPY mRNA were periprandial, with expression levels being significantly elevated at meal time (P less than 0.05) and significantly reduced 2 h later (P less than 0.05). Comparing the fasting and unfasted groups, NPY mRNA levels were significantly higher (P less than 0.05) at -2 h and +2 h in the fasting group, but there was no difference at 0 h. In addition, the higher NPY mRNA levels that were observed in the fasting group were maintained throughout the sampling period. In summary, our results show that NPY expression was associated with meal time (0 h) in food intake regulation.
Vinicius F Campos; Ricardo B Robaldo; Joao C Deschamps; Fabiana K Seixas; Alan John A McBride; Luis Fernando Marins; Marcelo Okamoto; Luis A Sampaio; Tiago Collares
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of biosciences     Volume:  37     ISSN:  0973-7138     ISO Abbreviation:  J. Biosci.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100809     Medline TA:  J Biosci     Country:  India    
Other Details:
Languages:  eng     Pagination:  227-32     Citation Subset:  IM    
Nucleo de Biotecnologia, Centro de Desenvolvimento Tecnologico, CP 354, 96010-900, Pelotas, RS, Brazil,
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