Document Detail


Neuropeptide Y and epilepsy: recent progress, prospects and controversies.
MedLine Citation:
PMID:  15337378     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neuropeptide Y (NPY), a 36 amino-acid member of the pancreatic polypeptide family, has received considerable attention in recent years as an endogenous modulator of epileptic activity. Prominently expressed in brain regions involved in seizure generation and propagation, NPY can exert powerful effects on synaptic transmission. Here, we discuss the anti-epileptic actions of NPY and receptor subtypes responsible.
Authors:
S C Baraban
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neuropeptides     Volume:  38     ISSN:  0143-4179     ISO Abbreviation:  Neuropeptides     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-31     Completed Date:  2005-05-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8103156     Medline TA:  Neuropeptides     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  261-5     Citation Subset:  IM    
Affiliation:
Epilepsy Research Laboratory, Department of Neurological Surgery, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA. baraban@itsa.ucsf.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / anatomy & histology,  metabolism
Epilepsy / metabolism*
Neuropeptide Y / metabolism*
Receptors, Neuropeptide Y / metabolism
Chemical
Reg. No./Substance:
0/Neuropeptide Y; 0/Receptors, Neuropeptide Y; 0/neuropeptide Y-Y1 receptor; 0/neuropeptide Y2 receptor; 0/neuropeptide Y5 receptor

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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