Document Detail


Neuropathological and anatomopathological analyses of acardiac and "normal" siblings in an acardiac-twin pregnancy.
MedLine Citation:
PMID:  12899203     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acardiac twinning is a very rare complication of multiple pregnancy. The authors present the neuropathological and anatomopathological description of the twins of the multiple pregnancy complicated by the acardiac foetus and terminated at 26 weeks of gestation. An anatomopathological examination of the "normal" twin showed hyaline membrane syndrome, cardiomegaly and hepatomegaly. Neuropathologically, numerous hypoxic-ischaemic lesions, most likely associated with haemodynamic disorders during pregnancy as well as less pronounced perinatal changes were revealed. The acardiac foetus, classified as acardius acephalus, demonstrated the presence of some abdominal organs and a histologically well-developed spinal cord. In view of the neuropathological changes, monitoring "normal" twins for discreet pathological central nervous system signs, which may be similar in character to those described, may play a significant role.
Authors:
Elzbieta Kosno-Kruszewska; Krzysztof Deregowski; Bogna Schmidt-Sidor; Teresa Wierzba-Bobrowicz; Barbara Pawłowska; Waldemar Lechowicz; Grazyna M Szpak; Eliza Lewandowska; Ewa Bertrand; Romana Bogusławska; Anna Tomankiewicz-Zawadzka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences     Volume:  41     ISSN:  1641-4640     ISO Abbreviation:  Folia Neuropathol     Publication Date:  2003  
Date Detail:
Created Date:  2003-08-05     Completed Date:  2003-09-02     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  9437431     Medline TA:  Folia Neuropathol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  103-9     Citation Subset:  IM    
Affiliation:
Department of Neuropathology, Institute of Psychiatry and Neurology, Warszawa, Poland. ekrusze@ipin.edu.pl
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Severe Teratoid / pathology*
Adult
Brain / abnormalities,  pathology*
Diseases in Twins / diagnosis*
Female
Fetal Diseases / pathology*
Heart Defects, Congenital / diagnosis,  pathology*
Humans
Pregnancy
Siblings
Twins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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