Document Detail


Neuropathies in the context of malignancies.
MedLine Citation:
PMID:  18769246     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: To conduct a critical review of recent data pertaining to the clinical and therapeutic aspects of peripheral neuropathies in the setting of malignancies, with the exception of paraproteinemic neuropathies. Our search extended to the past 2 years, using a PubMed search strategy. RECENT FINDINGS: In the field of neuropathies linked with the development of the cancer, recent works have focused on lymphoma and cancer-associated vasculitides. In paraneoplastic syndromes, the major fact of the past 2 years is the issue of guidelines for diagnosis and treatment of these disorders, under the aegis of the paraneoplastic syndromes Euronetwork and of the European Federation of Neurological Sciences. When considering chemotherapy, neurotoxicity is becoming increasingly better known. Finally, the spectrum of late-delayed complications of irradiation further increases with a better clinical characterization of radiotherapy-induced dropped head syndrome. SUMMARY: This article successively reviews the results of the recent studies in these various fields. In the field of chemotherapy, we will particularly focus on some new data concerning oxaliplatin, bortezomib, the albumin-bound form of paclitaxel and lenalidomide.
Authors:
Anthony Behin; Dimitri Psimaras; Khe Hoang-Xuan; Jean-Marc Leger
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current opinion in neurology     Volume:  21     ISSN:  1350-7540     ISO Abbreviation:  Curr. Opin. Neurol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-04     Completed Date:  2008-10-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9319162     Medline TA:  Curr Opin Neurol     Country:  England    
Other Details:
Languages:  eng     Pagination:  534-9     Citation Subset:  IM    
Affiliation:
APHP, Centre de référence de pathologie neuromusculaire Paris-Est, Bâtiment Babinski, Fédération de Neurologie Mazarin, GH Pitié-Salpêtrière, Paris, France. anthony.behin@psl.aphp.fr
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / pharmacology,  therapeutic use
Drug Therapy / adverse effects
Humans
Neoplasms* / pathology,  physiopathology,  therapy
Peripheral Nerves / drug effects,  pathology,  physiopathology,  radiation effects
Peripheral Nervous System Diseases / chemically induced,  pathology*,  physiopathology*
PubMed
Radiotherapy / adverse effects
Chemical
Reg. No./Substance:
0/Antineoplastic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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