Document Detail


Neuronal habituation in the vestibular nuclei of the cat.
MedLine Citation:
PMID:  7468180     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This is a study of the effects of repeated angular acceleration on the activity of vestibular nuclei units in anesthetized and in conscious cats. The experimental animals were subjected to trains of repeated and consecutive constant acceleration-deceleration ramps (4-8 degrees/sec2). In a few cases nystagmus was recorded along with extracellular unit activity. The effect of stimulus repetition on vestibular neuronal activity consisted of one of the following: 1. No change in response. 2. Progressive response decline. 3. An initial maintenance of a constant response level throughout the first part of the stimulus paradigm, followed by a progressive decline. 4. An initial gradual enhancement of response followed by a progressive decline. This classification is based on results of polynomial and non-linear broken-line regression analyses. Categories 3 and 4 were found predominantly in units recorded from conscious cats. The majority of neurons recorded from anesthetized cats that exhibited response changes upon stimulus repetition manifested a progressive response decline. The response decline in anesthetized cat units was usually on a faster time scale than in conscious cats. Correlations between unit response modification patterns and simultaneously recorded nystagmus were mostly of a moderate degree.
Authors:
P Kileny; J H Ryu; B F McCabe; P J Abbas
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  90     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:    1980 Sep-Oct
Date Detail:
Created Date:  1981-04-24     Completed Date:  1981-04-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  175-83     Citation Subset:  IM; S    
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MeSH Terms
Descriptor/Qualifier:
Acceleration
Anesthesia
Animals
Cats
Deceleration
Evoked Potentials
Eye Movements
Habituation, Psychophysiologic*
Vestibular Nuclei / physiology*
Grant Support
ID/Acronym/Agency:
NINDS06785/DS/DS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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