Document Detail


Neuron-specific enolase-like immunoreactivity in inner hair cells but not outer hair cells in the guinea pig organ of Corti.
MedLine Citation:
PMID:  3886070     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neuron-specific enolase (NSE) has been localized only in neurons and cells with characteristics of neurons. The immunocytochemical localization of NSE was examined in guinea pig cochleae to determine if hair cells, which have some neuronal characteristics, would show NSE-like immunoreactive labeling. NSE-like immunoreactivity was seen in inner hair cells but not in outer hair cells. This is the first report of NSE-like immunoreactivity in a receptor cell. NSE-like immunoreactivity was also seen in efferent fibers and terminals and in both type I and type II spiral ganglion cells. The finding of NSE-like immunoreactivity in inner but not outer cells adds to the number of differences found between them and may be related to differences in function and action.
Authors:
R A Altschuler; K A Reeks; P J Marangos; J Fex
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Brain research     Volume:  327     ISSN:  0006-8993     ISO Abbreviation:  Brain Res.     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-06-10     Completed Date:  1985-06-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0045503     Medline TA:  Brain Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  379-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Cochlea / immunology
Female
Fluorescent Antibody Technique
Ganglia / cytology
Guinea Pigs
Hair Cells, Auditory / immunology*
Hair Cells, Auditory, Inner / immunology*
Immunoenzyme Techniques
Microscopy, Fluorescence
Neurons / classification
Organ of Corti / immunology*
Phosphopyruvate Hydratase / immunology*
Chemical
Reg. No./Substance:
EC 4.2.1.11/Phosphopyruvate Hydratase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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