| Neuromyelitis optica. | |
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MedLine Citation:
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PMID: 15968305 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The combination of optic neuritis and myelitis, the so-called Neuromyelitis optica is an uncommon pattern of demyelinating disorder. In 1870, Sir Thomas Clifford Allbutt first reported the association and Erb published a comparable report. Gowers and Dreschfeld described other instances in the 19th century. This paper attempts to review the syndrome to consider whether it merits recognition as a disease, sui generis, or rather as a syndrome symptomatic of multiple sclerosis, acute disseminated encephalomyelitis, and other immunological disorders. Two forms are distinguished: a monophasic illness, and a relapsing form. The claimed differential features separating it from classical multiple sclerosis are appraised. Modern immunology suggests an antibody-dependent, complement-mediated pathogenesis. |
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Authors:
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J M S Pearce |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Spinal cord Volume: 43 ISSN: 1362-4393 ISO Abbreviation: Spinal Cord Publication Date: 2005 Nov |
Date Detail:
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Created Date: 2005-11-07 Completed Date: 2006-02-07 Revised Date: 2011-06-06 |
Medline Journal Info:
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Nlm Unique ID: 9609749 Medline TA: Spinal Cord Country: England |
Other Details:
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Languages: eng Pagination: 631-4 Citation Subset: IM |
Copyright Information:
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Spinal Cord (2005) 43, 631-634. doi:10.1038/sj.sc.3101758; published online 14 June 2005. |
Affiliation:
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Department of Neurology, Hull Royal Infirmary, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Neuromyelitis Optica / classification, diagnosis*, physiopathology*, therapy |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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