| Neuromyelitis optica: clinical manifestations and neuroimaging features. | |
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MedLine Citation:
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PMID: 23186898 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Neuromyelitis optica (NMO) is a severe inflammatory demyelinating disease of the central nervous system with distinguishing features from multiple sclerosis. Understanding of clinical presentation, immunopathology, and imaging features has changed during the last decade. The identification of NMO immunoglobulin G and aquaporin 4 as the target antigen in this disease helped to define the NMO spectrum of disorders and showed that NMO is an autoimmune channelopathy of the central nervous system. Several types of brain involvement have been described in patients with NMO. This article discusses the epidemiology, clinical manifestations, and immunopathogenesis of the disease with an emphasis on neuroimaging. |
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Authors:
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Mohammad Ali Sahraian; Ernst-Wilhelm Radue; Alireza Minagar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurologic clinics Volume: 31 ISSN: 1557-9875 ISO Abbreviation: Neurol Clin Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2012-11-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8219232 Medline TA: Neurol Clin Country: United States |
Other Details:
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Languages: eng Pagination: 139-52 Citation Subset: IM |
Copyright Information:
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Copyright © 2013. Published by Elsevier Inc. |
Affiliation:
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Sina MS Research Center, Iranian Center for Neurological Research, Sina Hospital, Hassan abad Square, Tehran, Iran. Electronic address: msahrai@sina.tums.ac.ir. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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