Document Detail


Neuromyelitis optica - Devic's syndrome, update.
MedLine Citation:
PMID:  17027889     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neuromyelitis optica of Devic (NMO) is a syndrome which combines transverse myelitis and optic neuritis. For many years it was assumed that transverse myelitis and optic neuritis should be simultaneous, that optic neuritis should be bilateral, and that transverse myelitis must be complete. NMO was considered to be very rare. Through the 20th century there was a debate on whether NMO is a distinct nosologic entity or a form of MS. In 2005 it is now possible to distinguish NMO from MS on the basis of the clinical, imaging, serology and immunopathology profile. This distinction is necessary for the implementation of adequate treatments, as the relapsing form of the illness carries significant morbidity and mortality.
Authors:
Raul N Mandler
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Publication Detail:
Type:  Journal Article; Review     Date:  2006-03-21
Journal Detail:
Title:  Autoimmunity reviews     Volume:  5     ISSN:  1568-9972     ISO Abbreviation:  Autoimmun Rev     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-09     Completed Date:  2007-02-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128967     Medline TA:  Autoimmun Rev     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  537-43     Citation Subset:  IM    
Affiliation:
MS Center, George Washington University, USA. raulmandler@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Causality
Comorbidity
Humans
Multiple Sclerosis* / diagnosis,  epidemiology,  pathology
Neuromyelitis Optica* / diagnosis,  epidemiology,  pathology
Recurrence

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