Document Detail

Neuromuscular symptoms in elderly patients with hyperparathyroidism: improvement with parathyroid surgery.
MedLine Citation:
PMID:  3393114     Owner:  NLM     Status:  MEDLINE    
In a consecutive series of 100 neck explorations for primary hyperparathyroidism, 42 patients were 60 years of age or older; in this group of elderly patients the surgical cure rate was 100%. These patients were reviewed retrospectively by means of a structure interview. Twenty-one patients had had preoperative neuromuscular symptoms that ranged from coma to subjective muscular weakness. These patients had significantly-higher preoperative serum calcium and parathyroid hormone levels than did 21 patients without neuromuscular symptoms (P = 0.003 and P = 0.046, respectively). Most of the neuromuscular symptoms improved in the postoperative period. In particular, 15 of 17 patients with muscle weakness reported a significant improvement, while 14 of 15 patients who suffered from fatigue and lethargy reported an improvement. An improvement also occurred in the level of day-to-day function in eight patients. While surgery for primary hyperparathyroidism generally is undertaken for a specific indication, such as severe hypercalcaemia or renal stones, it appears from this study that neuromuscular symptoms also may improve, particularly in elderly patients.
L W Delbridge; D Marshman; T S Reeve; P Crummer; S Posen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  149     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  1988 Jul 
Date Detail:
Created Date:  1988-08-18     Completed Date:  1988-08-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  74-6     Citation Subset:  IM    
University of Sydney Department of Surgery, Royal North Shore Hospital of Sydney, St Leonards, NSW.
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MeSH Terms
Aged, 80 and over
Hyperparathyroidism / complications,  surgery*
Middle Aged
Neuromuscular Diseases / etiology*,  physiopathology
Parathyroid Glands / surgery*
Postoperative Complications
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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