Document Detail

Neurological manifestations of acute granulocytic leukemia.
MedLine Citation:
PMID:  4525937     Owner:  NLM     Status:  MEDLINE    
Of 17 consecutive patients with acute granulocytic leukemia, all of whom were treated with cytosine arabinoside, eight had neurological complications during some stage of their disease. This high occurrence of neurological findings represents a significant increase compared with the authors' experience and, in general, with that cited in the literature. The neurological findings were usually related to significant morbidity and to mortality. Early recognition of neurological problems depends mainly upon clinical and cerebrospinal fluid findings. Progression of neurological manifestations, which can be satisfactorily treated with radiotherapy or neurosurgical methods, may result in unnecessary morbidity and premature death.
S A Armentrout; R F Ulrich
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Western journal of medicine     Volume:  121     ISSN:  0093-0415     ISO Abbreviation:  West. J. Med.     Publication Date:  1974 Jul 
Date Detail:
Created Date:  1974-09-03     Completed Date:  1974-09-03     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410504     Medline TA:  West J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
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MeSH Terms
Leukemia, Myeloid, Acute / complications*
Middle Aged
Neurologic Manifestations*

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