| Neurological manifestations of HIV infection. | |
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MedLine Citation:
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PMID: 12657756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Case records of HIV infected patients were analyzed for identifying neurological manifestations. Eight patients (7 males) were identified to have probable HIV encephalopathy (in a period of 24 months) as per the CDC revised classification system. Their ages ranged from one year to ten years. The neurological manifestations noted included-developmental delay (2 cases), seizures (6 cases), acute onset alteration of sensorium (4 cases), aphasia (2 cases), loss of vision (2 cases), focal neurological deficits (6 cases), brisk deep tendon reflexes (7 cases), extensor plantar responses (5 cases) and signs of cerebellar dysfunction (2 cases). Other clinical features included growth failure, microcephaly, fever, lymphadenopathy, hepatomegaly, splenomegaly, pneumonia, otorrhea and oral candidiasis. Cerebrospinal fluid studies were normal. The neuroimaging features included cerebral atrophy and ventricular dilatation, cerebral infarction, basal ganglia calcification and cerebellar atrophy. Childhood HIV infection may have a variety of neurological abnormalities. HIV infection should be suspected in children presenting with unexplained neurological manifestations and growth failure. |
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Authors:
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Vardhaman S Udgirkar; Milind S Tullu; Sandeep B Bavdekar; Vijayalaxmi B Shaharao; Jaishree R Kamat; Priya R Hira |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian pediatrics Volume: 40 ISSN: 0019-6061 ISO Abbreviation: Indian Pediatr Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-03-26 Completed Date: 2003-05-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2985062R Medline TA: Indian Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 230-4 Citation Subset: IM |
Affiliation:
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Departments of Pediatrics and Radiology, Seth G.S. Medical College and KEM Hospital, Parel, Mumbai 400 012, Maharashtra, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Child, Preschool Female HIV Infections / complications*, diagnosis* Humans Male Nervous System Diseases / diagnosis*, etiology* Retrospective Studies |
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