Document Detail


Neurological differences between 9-year-old children fed breast-milk or formula-milk as babies.
MedLine Citation:
PMID:  7968027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The presence of minor neurological dysfunction is associated with behavioural and cognitive development at school age. We have previously shown a relation between minor neurological dysfunction and perinatal disorders, especially abnormal neonatal neurological condition. We have now investigated the relation between breastfeeding and long-term neurological development. We studied 135 breastfed (for > or = 3 weeks) and 391 formula-fed children, born at term in the University Hospital Groningen between 1975 and 1979. A standard neonatal neurological examination was used to classify the infants as normal (247), slightly abnormal (213), or frankly abnormal (66). At 9 years of age the children were reexamined. In 1993 their mothers were asked to complete a questionnaire about how the children were fed as infants. After adjustment for obstetric, perinatal, neonatal neurological, and social differences, a small advantageous effect of breastfeeding on neurological status at 9 years of age was found (odds ratio for neurological non-normality 0.54 [95% CI 0.30-0.97]). Although a retrospective design cannot lead to definite conclusions, our data suggest a beneficial effect of breast-feeding on postnatal neurological development. Longer-chain polyunsaturated fatty acids, which are present in breast-milk but not in most formula-milks, may have a role since they are vital for brain development.
Authors:
C I Lanting; V Fidler; M Huisman; B C Touwen; E R Boersma
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Lancet     Volume:  344     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1994-12-13     Completed Date:  1994-12-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1319-22     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynaecology, University Hospital Groningen, Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Bottle Feeding*
Breast Feeding*
Child
Child Development*
Cohort Studies
Female
Follow-Up Studies
Humans
Infant
Infant, Newborn
Male
Nervous System Diseases / diagnosis
Neurologic Examination*
Prospective Studies
Comments/Corrections
Comment In:
Lancet. 1995 Feb 11;345(8946):393   [PMID:  7845146 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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