| Neurological complications and pleural lavage with a fibrinolytic agent. A two-case report. | |
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MedLine Citation:
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PMID: 10990118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report on an unusual, albeit potentially severe, complication of the performance of a pleural lavage with streptokinase in two patients demonstrating parapneumonic pleural effusion. During the time they underwent repeated pleural lavages with saline and streptokinase, they suddenly demonstrated focal neurological signs. As a result of early diagnosis and emergency hyperbaric oxygenation, both patients recovered without delayed sequelae. Air embolism is a potentially severe complication which can occur during pleural lavage. Whether streptokinase increases the risk of opening a latent vascular breach cannot be definitely established, but clinicians should be aware of this risk. In this context, the onset of acute focal neurological signs should suggest the possibility of air embolism and lead to the transfer of the patient close to a hyperbaric facility within a few hours. |
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Authors:
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F Schneider; R Lion; C Kummerlen; X Ducrocq; J D Tempé |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Intensive care medicine Volume: 26 ISSN: 0342-4642 ISO Abbreviation: Intensive Care Med Publication Date: 2000 Jul |
Date Detail:
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Created Date: 2000-12-15 Completed Date: 2001-01-04 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7704851 Medline TA: Intensive Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 995-7 Citation Subset: IM |
Affiliation:
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Réanimation Médicale, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, France. Francis.Schneider@chru-strasbourg.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bronchoalveolar Lavage / adverse effects* Embolism, Air / complications, etiology* Fibrinolytic Agents / administration & dosage* Humans Male Middle Aged Nervous System Diseases / etiology* Streptokinase / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Fibrinolytic Agents; EC 3.4.-/Streptokinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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