Document Detail

Neurological complications and myelographic features of achondroplasia.
MedLine Citation:
PMID:  752129     Owner:  NLM     Status:  MEDLINE    
The neurological complications of achondroplasia are discussed based on the literature and two of our cases. Thoracolumbar kyphosis, hypertrophic osteoarthritis, and intervertebral disc herniations may cause early neurological disturbances to adult achondroplasts owing to the spinal stenosis. The symptoms range from nerve root compression syndromes to complete transverse myelopathy. The radiographic features are characteristic, but the value of myelography for etiological clarification and location of the pathological process is limited. The significance of early symptoms and signs must be stressed and early decompression performed, as results are very disappointing once extensive neurological damage has occurred. An extensive laminectomy is usually indicated.
M Galanski; R Herrmann; U Knoche
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuroradiology     Volume:  17     ISSN:  0028-3940     ISO Abbreviation:  Neuroradiology     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-08-16     Completed Date:  1979-08-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  59-63     Citation Subset:  IM    
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MeSH Terms
Achondroplasia / complications,  radiography*
Infant, Newborn
Middle Aged
Nerve Compression Syndromes / etiology
Nervous System Diseases / etiology*,  radiography
Spinal Cord Compression / etiology
Spine / radiography

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