Document Detail


Neurological complications of hematopoietic stem cell transplantation (HSCT): a retrospective study in a HSCT center in Brazil.
MedLine Citation:
PMID:  18949262     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present the neurological complications evaluated in a series of 1000 patients who underwent hematopoietic stem cell transplantation (HSCT). Central nervous system (CNS) neurological complications, particularly brain hemorrhages, were the most common, followed by seizures and CNS infections. An unusual neurological complication was Wernicke's encephalopathy. Less frequent neurological complications were metabolic encephalopathy, neuroleptic malignant syndrome, reversible posterior leukoencephalopathy syndrome, brain infarct and movement disorders. The most common neurological complication of the peripheral nervous system was herpes zoster radiculopathy, while peripheral neuropathies, inflammatory myopathy and myotonia were very rarely found.
Authors:
Hélio A G Teive; Vaneuza Funke; Marco A Bitencourt; Michel Michels de Oliveira; Carmen Bonfim; José Zanis-Neto; Carlos R de Medeiros; Viviane F Zétola; Lineu César Werneck; Ricardo Pasquini
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  66     ISSN:  1678-4227     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-24     Completed Date:  2009-08-19     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  685-90     Citation Subset:  IM    
Affiliation:
Neurology Service, Internal Medicine Department, Hospital de Clínicas, Federal University of Paraná, Curitiba, PR, Brazil. hagteive@mps.com.br
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Central Nervous System Diseases / classification,  etiology*
Child
Child, Preschool
Female
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Male
Middle Aged
Retrospective Studies
Young Adult

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