| Neurological complications of endemic skeletal fluorosis, with special emphasis on radiculo-myelopathy. | |
| | |
MedLine Citation:
|
PMID: 2172892 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The results of surveys carried out between 1976 and 1985 in the fluorosis-endemic area of the Ethiopian Rift Valley is summarised, with emphasis on the neurological complications resulting from the crippling osteofluorosis. The neurological manifestations in the forms of myelopathy with and without radiculopathy (respectively 72% and 28%) occurred after exposure to high fluoride (greater than 4 ppm) for longer than 10 years. These deficits were clearly found to be a consequence of fluoride deposition in bones, resulting in generalised sclerosis and osteophytosis, with reduction in the diameter of the intervertebral foramina and of the spinal conal. Advanced osteosclerosis commonly causes severe spastic quadriparesis in flexion, accompanied by distressing spasms and urinary incontinence. The dilemma of these medical problems in relation to the agro-industrial economic developments of the Ethiopian Rift Valley is discussed. |
| | |
Authors:
|
R T Haimanot |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Paraplegia Volume: 28 ISSN: 0031-1758 ISO Abbreviation: Paraplegia Publication Date: 1990 May |
Date Detail:
|
Created Date: 1990-12-06 Completed Date: 1990-12-06 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 2985038R Medline TA: Paraplegia Country: SCOTLAND |
Other Details:
|
Languages: eng Pagination: 244-51 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine, Faculty of Medicine, Addis Ababa University, Ethiopia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Agriculture Bone Diseases / chemically induced* Carbohydrates Chronic Disease Ethiopia Female Fluorine / poisoning* Humans Laminectomy Male Middle Aged Nervous System Diseases / etiology* Peripheral Nervous System Diseases / etiology Spinal Canal* Spinal Cord Compression / chemically induced, surgery Spinal Diseases / etiology Spinal Nerve Roots* |
| Chemical | |
Reg. No./Substance:
|
0/Carbohydrates; 7782-41-4/Fluorine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Parvovirus B 19 infection and associated arthritis in children and adolescents
Next Document: Effects of estrogen treatment on the antiviral properties of murine Kupffer cells