Document Detail

Neurological complications after thrombolytic treatment for acute myocardial infarction: emphasis on unprecedented manifestations.
MedLine Citation:
PMID:  1621495     Owner:  NLM     Status:  MEDLINE    
We examined 348 patients who underwent thrombolytic treatment for acute myocardial infarction. Nine patients (2.58%) developed neurological complications related directly or indirectly to this procedure. Cerebral hemorrhage occurred in 3 patients; 2 patients had transient ischemic attacks, 1 had syncope, another had psychomotor agitation and 2 patients presented seizures during the infusion of the thrombolytic agent, without hemodynamic abnormalities. This latter feature had never been described before.
P Caramelli; E G Mutarelli; B Caramelli; B Tranchesi; F Pileggi; M Scaff
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  85     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-08-06     Completed Date:  1992-08-06     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  331-3     Citation Subset:  IM    
Department of Neurology, University of São Paulo, Brazil.
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MeSH Terms
Brain Diseases / drug therapy,  etiology,  physiopathology
Cerebrovascular Disorders / drug therapy,  etiology
Enzyme Activation
Fibrinolytic Agents / diagnostic use*
Heparin / administration & dosage,  diagnostic use*
Middle Aged
Myocardial Infarction / complications,  physiopathology,  therapy*
Phenytoin / therapeutic use
Seizures / drug therapy,  etiology,  physiopathology
Thrombolytic Therapy*
Tissue Plasminogen Activator / administration & dosage,  diagnostic use*
Reg. No./Substance:
0/Fibrinolytic Agents; 57-41-0/Phenytoin; 9005-49-6/Heparin; EC Plasminogen Activator

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