Document Detail


A Neurological Complication of a Uterine Fibroid.
MedLine Citation:
PMID:  22045247     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: Uterine leiomyoma (or fibroid) can be associated with secondary polycythemia and venous thrombosis, but there has been no report of intracranial venous thrombosis associated with leiomyoma. METHODS: We describe a case report of a cerebral venous thrombosis associated with erythrocytosis and a uterine fibroid in a non-smoking female with no history of malignancy or hormone use. The hemoglobin and erythropoietin normalized after removal of her uterine fibroid. RESULTS: MRI/MRV of this 60-year-old cephalalgic female revealed extensive thrombus throughout the sagittal sinus and right transverse sinus. CT of the abdomen revealed a 16 × 13 × 12 cm solid mass arising for the uterus consistent with a uterine fibroid. PET scan was negative for malignancy. Hemoglobin on admission was 18.4 g/dl. Erythropoietin was 16.6 mIU/ml. One month after hysterectomy, her hemoglobin was 12.6 g/dl and her erythropoietin was 4.7 mIU/ml. CONCLUSIONS: Cerebral vein thrombosis is a potential complication of uterine fibroids with erythrocytosis.
Authors:
Jonathan Graff-Radford; David T Jones; Rajiv K Pruthi; Kelly D Flemming
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-11-2
Journal Detail:
Title:  Neurocritical care     Volume:  -     ISSN:  1556-0961     ISO Abbreviation:  -     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156086     Medline TA:  Neurocrit Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
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