Document Detail

Neurologic symptoms are common during gestation and puerperium in CADASIL.
MedLine Citation:
PMID:  15851739     Owner:  NLM     Status:  MEDLINE    
Based on a structured questionnaire and medical records, the authors found that 12 of 25 mothers with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) with the R133C NOTCH3 mutation had had neurologic symptoms in 17 of their 43 pregnancies, most commonly hemiparesthesia (76%), hemiparesis (36%), aphasia (65%), and visual disorders (47%). In 82% of the patients, the symptoms were the first manifestation of CADASIL. The symptoms were most common during puerperium and in patients older than age 30.
S Roine; M Pöyhönen; S Timonen; S Tuisku; R Marttila; R Sulkava; H Kalimo; M Viitanen
Related Documents :
1141959 - Reversible central nervous system dysfunction in folate deficiency.
8815159 - Neurological impairment and recovery in wilson's disease: evidence from pet and mri.
11232699 - Focal neurological signs in hepatic encephalopathy in cirrhotic patients: an underestim...
19234759 - Disorders of biopterin metabolism.
6093189 - Cerebral metastases from lung carcinoma: neurological and ct correlation. work in progr...
9444579 - Efficacy of conservative treatment of lumbar disc herniation.
20444959 - Breakfast improves cognitive function in cirrhotic patients with cognitive impairment.
24267509 - A prospective observational study of associated anomalies in hirschsprung's disease.
14675059 - Prevalence of anemia in erythropoietin-treated pediatric as compared to adult chronic d...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurology     Volume:  64     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-04-26     Completed Date:  2006-01-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1441-3     Citation Subset:  AIM; IM    
Department of Neurology, University and University Hospital of Turku, Finland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aphasia / epidemiology
Brain / blood supply,  pathology,  physiopathology
Brain Ischemia / epidemiology,  physiopathology*
CADASIL / epidemiology,  genetics,  physiopathology*
Cerebral Arteries / pathology,  physiopathology
Cohort Studies
Cross-Sectional Studies
Finland / epidemiology
Paresis / epidemiology
Paresthesia / epidemiology
Postpartum Period
Pre-Eclampsia / epidemiology
Pregnancy Complications / epidemiology,  physiopathology*
Retrospective Studies
Vision Disorders / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Somatotopically located motor fibers in corona radiata: evidence from subcortical small infarcts.
Next Document:  EGFR tyrosine kinase domain mutations in human gliomas.