Document Detail


Neurologic and radiologic manifestations of three girls surviving acute carbon monoxide poisoning.
MedLine Citation:
PMID:  16970876     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the neurologic and radiologic manifestations of three adolescent girls with acute carbon monoxide poisoning. The girls were found collapsed and unconscious in a bathroom where liquid petroleum gas was being used as heating fuel. As hyperbaric oxygen therapy was not available locally, they only received oxygen supplementation via nasal cannula (4 L/minute) as treatment in the first 2 days. On transfer to a tertiary center in Hong Kong, evolving neurologic manifestations of visual acuity and field deficits, confusion, and focal motor weaknesses were observed. Focal infarctions were evident in cerebral computed tomography in one patient and cortical lesions on magnetic resonance imaging in all three patients. [18F]Fluorodeoxyglucose (FDG) positron emission tomography (PET) revealed additional decreased metabolism in the basal ganglia in two patients, which was typical of carbon monoxide poisoning. The neurologic deficits resolved completely at 3 weeks after the exposure, but psychologic symptoms succeeded. This report serves to alert clinicians to the varied neuro-ophthalmologic manifestations and psychologic impairment even with the same duration of carbon monoxide poisoning. PET might be more sensitive in detecting cerebral injuries specific for carbon monoxide poisoning.
Authors:
Kam-lun Ellis Hon; Wai-lan Yeung; Chi-hang Assunta Ho; Wing-kwan Alex Leung; Albert Martin Li; Winnie Chiu-wing Chu; Yu-leung Chan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  21     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-14     Completed Date:  2006-12-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  737-41     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Chinese University of Hong Kong, 6/F Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong. ehon@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Basal Ganglia / metabolism*,  pathology
Carbon Monoxide Poisoning / complications*,  radiography,  radionuclide imaging,  therapy
Cerebral Cortex / metabolism,  pathology,  radiography,  radionuclide imaging
Cerebral Infarction / etiology*,  radiography,  radionuclide imaging
Child
Confusion / etiology*,  physiopathology
Female
Humans
Oxygen Inhalation Therapy
Positron-Emission Tomography
Survivors
Time Factors
Tomography, X-Ray Computed
Treatment Outcome
Vision Disorders / etiology*,  physiopathology

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