Document Detail


Neurologic outcome in neonatal temporal lobe hemorrhagic venous infarcts.
MedLine Citation:
PMID:  19574579     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Consequences of neonatal cerebral venous infarct can be severe. However, we have identified a series of neonates with unilateral temporal lobe infarcts, suspected to be secondary to superficial cortical venous thrombosis, who have had relatively normal outcomes. Medical records were reviewed retrospectively. History, relevant studies, and outcomes for 7 patients are described. Most patients presented with neonatal seizures. Neuroimaging showed unilateral temporal lobe hemorrhage and surrounding ischemic change, which was initially attributed to thrombosis of the vein of Labbe; however, magnetic resonance venogram findings suggest that thrombosis of other superficial temporal lobe veins may also be involved. Seizure control was achieved in all cases. Development and neurologic examination at follow-up were usually normal. We conclude that neonatal temporal lobe hemorrhagic infarct secondary to suspected superficial temporal venous thrombosis appears to have a good clinical outcome. This is surprising, given the dramatic imaging and clinical presentations.
Authors:
Laurel Slaughter; John Egelhoff; Tonya Balmakund
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Publication Detail:
Type:  Journal Article     Date:  2009-07-02
Journal Detail:
Title:  Journal of child neurology     Volume:  24     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-06     Completed Date:  2010-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1236-42     Citation Subset:  IM    
Affiliation:
Division of Child Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA. laurel.slaughter@cchmc.org
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MeSH Terms
Descriptor/Qualifier:
Anticonvulsants / therapeutic use
Brain Infarction / pathology*,  physiopathology,  therapy*
Electroencephalography
Female
Follow-Up Studies
Functional Laterality
Humans
Infant, Newborn
Intracranial Hemorrhages / pathology*,  physiopathology,  therapy*
Magnetic Resonance Imaging
Phlebography
Retrospective Studies
Seizures / pathology,  physiopathology,  therapy
Temporal Lobe / blood supply,  pathology*
Treatment Outcome
Venous Thrombosis / pathology,  physiopathology,  therapy
Chemical
Reg. No./Substance:
0/Anticonvulsants

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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