Document Detail

Neurologic manifestations of Schoenlein-Henoch purpura: report of three cases and review of the literature.
MedLine Citation:
PMID:  2984637     Owner:  NLM     Status:  MEDLINE    
Three patients developed prominent neurologic symptoms and signs associated with Schoenlein-Henoch purpura. A 7 1/2-year-old boy was seen with status epilepticus after a 2-week history of generalized headaches, irritability, and intermittent colicky abdominal pain. A left hemiparesis and a left homonymous hemianopia with a right gaze preference that were present on initial examinations gradually resolved, but a mild left arm paresis persisted. Cutaneous, renal, and joint involvement followed initial CNS manifestations. The second patient, a 7-year-old girl, had a complex partial seizure with secondary generalization and a postictal hemiparesis seven days after presentation with classic signs of Schoenlein-Henoch purpura. Behavioral changes were noted during the acute phase of the illness. The third patient, a 13-year-old boy, developed signs of a left brachial plexopathy and transient weakness of his right leg during a complicated course of Schoenlein-Henoch purpura. Review of the world literature indicates that headaches and mental status changes are the most frequent neurologic complications of Schoenlein-Henoch purpura, followed by seizures, focal neurologic deficits, mononeuropathies, and polyradiculoneuropathies. The vasculitis of Schoenlein-Henoch purpura can involve the nervous system and may add significantly to the morbidity of the illness.
A L Belman; C R Leicher; S L Moshé; A P Mezey
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Pediatrics     Volume:  75     ISSN:  0031-4005     ISO Abbreviation:  Pediatrics     Publication Date:  1985 Apr 
Date Detail:
Created Date:  1985-05-07     Completed Date:  1985-05-07     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  687-92     Citation Subset:  AIM; IM    
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MeSH Terms
Brain Diseases / etiology
Headache / etiology
Nervous System Diseases / etiology*,  pathology
Paralysis / etiology
Peripheral Nervous System Diseases / etiology
Purpura, Schoenlein-Henoch / complications*,  pathology
Seizures / etiology
Status Epilepticus / etiology
Grant Support

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