Document Detail


Neurologic manifestations of Fusobacterium infections in children.
MedLine Citation:
PMID:  23015047     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Fusobacterium necrophorum causes various clinical syndromes, ranging from otitis media to life-threatening Lemierre's syndrome. The purpose of this study was to review our experience with pediatric Fusobacterium infections. The medical records of all children aged 0 to 18 years who were diagnosed between 1999 and 2011 with Fusobacterium infection were reviewed. Fusobacterium was isolated from clinical samples of 27 children: blood cultures (n = 16), abscesses (n = 8), joint fluids (n = 2), and cerebrospinal fluid (n = 1). The median age at admission was 3.5 years (range, 7 months to 17 years). Eight children (30 %) had seizures at presentation. Ten children (37 %) underwent lumbar puncture. Fifteen children (56 %) underwent brain imaging, and in seven of these children, a thrombus was identified either in a sinus vein or in an internal jugular vein. The most common source of infection was otogenic in 19 (70 %) of the children. Six of the children presented in 2011. All patients recovered. Conclusions: Neurologic manifestations are common at presentation of children with Fusobacterium infections. In young children, the most common source of infection is otogenic. Thrombotic complications are common, and imaging should be considered in all children with Fusobacterium infections arising from the head or neck region. There was a recent increase in the isolation of this bacterium, either because of better culturing techniques and increased awareness to this entity or a true increase in infections due to this organism.
Authors:
Orli Megged; Marc V Assous; Hagit Miskin; Uri Peleg; Yechiel Schlesinger
Related Documents :
24343607 - Surveillance for rotavirus gastroenteritis in children less than 5 years of age in togo.
17984817 - Epidemiology and clinical presentation of shigellosis in children less than five years ...
23152337 - Surveillance of influenza a h1n1 2009 among school children during 2009 and 2010 in sã...
23074117 - Xanthogranulomatous pyelonephritis in korean children.
17363397 - The problems in scaling adult drug doses to children.
21338007 - Media and children's aggression, fear, and altruism.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-27
Journal Detail:
Title:  European journal of pediatrics     Volume:  -     ISSN:  1432-1076     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Pediatric Department and Pediatric Infectious Diseases Unit, Shaare Zedek Medical Center, Hadassah-Hebrew University Medical School, P.O.B. 3235, Jerusalem, Israel, orlimegged@yahoo.com.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Association of adipokines with cardiovascular risk factors in low birth weight children: a case-cont...
Next Document:  Adults with autism: outcomes, family effects, and the multi-family group psychoeducation model.