Document Detail


Neurologic disease in Sjögren's syndrome: mononuclear inflammatory vasculopathy affecting central/peripheral nervous system and muscle. A clinical review and update of immunopathogenesis.
MedLine Citation:
PMID:  8265827     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is a growing appreciation that a subset of patients with primary Sjögren's syndrome (SS) also may develop a spectrum of central nervous system (CNS) complications. This article defines SS and its significance; discusses CNS, peripheral nervous system, and muscular complications of SS; identifies those areas in general or internal medicine in which SS patients with potential neurologic complications may present; describes those neurologic disorders that SS may mimic; places into perspective the controversy regarding the frequency and significance of CNS-SS; and extends our observations on the immunopathogenesis of neurologic complications in SS.
Authors:
E L Alexander
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Rheumatic diseases clinics of North America     Volume:  19     ISSN:  0889-857X     ISO Abbreviation:  Rheum. Dis. Clin. North Am.     Publication Date:  1993 Nov 
Date Detail:
Created Date:  1994-01-25     Completed Date:  1994-01-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8708093     Medline TA:  Rheum Dis Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  869-908     Citation Subset:  IM    
Affiliation:
Division of Molecular and Clinical Rheumatology, Johns Hopkins Medical Institutions, Baltimore, Maryland.
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MeSH Terms
Descriptor/Qualifier:
Autoantibodies
Central Nervous System Diseases / immunology*
Humans
Muscular Diseases / immunology*
Peripheral Nervous System Diseases / immunology*
Sjogren's Syndrome / complications*
Vasculitis / immunology*
Chemical
Reg. No./Substance:
0/Autoantibodies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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