Document Detail


Neurologic abnormalities in two patients with facial hemiatrophy and sclerosis coexisting with morphea.
MedLine Citation:
PMID:  9144696     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Progressive facial hemiatrophy or Parry-Romberg syndrome is a rare entity characterized by unilateral atrophy of the skin, subcutaneous tissue, and the underlying bony structures. This syndrome has many features of linear scleroderma en coup de sabre but is distinguished by more extensive involvement of the lower face and by only slight cutaneous sclerosis. We describe two unusual children with both atrophic and sclerotic changes of half of the face coexisting with multiple plaques of typical morphea. Both children developed neurologic disturbances with cranial magnetic resonance imaging (MRI) abnormalities 2 years and 15 years, respectively, after the onset of cutaneous lesions. Thus considering that it may not be possible to correlate impairment in neurologic function and cutaneous disease, as illustrated by our patients, we emphasize the importance of an accurate follow-up.
Authors:
S Menni; A V Marzano; E Passoni
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  14     ISSN:  0736-8046     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    1997 Mar-Apr
Date Detail:
Created Date:  1997-07-15     Completed Date:  1997-07-15     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  113-6     Citation Subset:  IM    
Affiliation:
Institute of Dermatological Sciences, University of Milan, IRCCS Ospedale Maggiore, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cerebral Infarction / complications*,  diagnosis
Facial Hemiatrophy / complications*,  diagnosis
Female
Humans
Magnetic Resonance Imaging
Male
Scleroderma, Localized / complications*,  pathology
Skin / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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