Document Detail

Neurologic and muscular complications of the 2009 influenza A (H1N1) pandemic.
MedLine Citation:
PMID:  20697982     Owner:  NLM     Status:  MEDLINE    
In the spring of 2009 a new triple-reassortant of influenza A (H1N1) virus appeared in Mexico and rapidly spread around the world, becoming a pandemic that primarily infected children and uncommonly older adults. Accompanying the pandemic were associated neurologic and muscular syndromes that affected primarily children and included febrile seizures, encephalopathy/encephalitis with or without seizures, delirium, focal neurologic syndromes, Guillain-Barré syndrome, myositis, and myocarditis. Neither the frequency nor the severity of these syndromes appears different from those recognized during periods of infections of previous influenza A viruses. I review the clinical, laboratory, neuroimaging, and pathologic characteristics of the associated syndromes appearing in the first wave of the pandemic, compare them to similar cases occurring in previous years, and explore several theories of pathogenesis.
Larry E Davis
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current neurology and neuroscience reports     Volume:  10     ISSN:  1534-6293     ISO Abbreviation:  Curr Neurol Neurosci Rep     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-21     Completed Date:  2011-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100931790     Medline TA:  Curr Neurol Neurosci Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  476-83     Citation Subset:  IM    
Neurology Service (127), New Mexico VA Health Care System, Albuquerque, NM 87108, USA.
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MeSH Terms
Influenza A Virus, H1N1 Subtype*
Influenza, Human / complications*,  epidemiology*
Muscular Diseases / complications*,  epidemiology*,  etiology
Nervous System Diseases / complications*,  epidemiology*,  etiology

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