| Neuroleptic malignant syndrome without fever after addition of oxcarbazepine to long-term treatment with amisulpride. | |
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MedLine Citation:
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PMID: 18774435 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Our goal was to report a case of malignant neuroleptic syndrome in a patient administered with both oxcarbazepine (OXCBZ) and amisulpride (AM). METHOD: We present a case of a young man who presented with symptoms of malignant neuroleptic syndrome after progressive titration of OXCBZ (1,200 mg) added to the long-term treatment with AM (800 mg). RESULTS: After discontinuation of AM and administration of dopaminergic drugs, his clinical symptoms improved gradually. CONCLUSION: This case suggests that clinicians should consider the risk of neuroleptic malignant syndrome when OXCBZ is coadministered to patients undergoing long-term treatment with neuroleptics. |
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Authors:
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Petros Angelopoulos; Maria Markopoulou; Kyriakos Kyamidis; Konstantinos Bobotas |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2008-07-23 |
Journal Detail:
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Title: General hospital psychiatry Volume: 30 ISSN: 0163-8343 ISO Abbreviation: Gen Hosp Psychiatry Publication Date: 2008 Sep-Oct |
Date Detail:
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Created Date: 2008-09-08 Completed Date: 2009-01-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7905527 Medline TA: Gen Hosp Psychiatry Country: United States |
Other Details:
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Languages: eng Pagination: 482-4 Citation Subset: IM |
Affiliation:
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General Hospital of Thessaloniki, Greece. petrosangelopoulos@yahoo.gr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anticonvulsants / adverse effects*, therapeutic use Antipsychotic Agents / adverse effects*, therapeutic use Carbamazepine / adverse effects, analogs & derivatives*, therapeutic use Chronic Disease Drug Therapy, Combination Humans Male Neuroleptic Malignant Syndrome / diagnosis, etiology* Schizophrenia / drug therapy* Sulpiride / adverse effects, analogs & derivatives*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 0/Antipsychotic Agents; 15676-16-1/Sulpiride; 28721-07-5/oxcarbazepine; 298-46-4/Carbamazepine; 53583-79-2/sultopride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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