| Neuroleptic malignant syndrome and serotonin syndrome in a female patient: a clinicopathologic case. | |
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MedLine Citation:
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PMID: 19820435 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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We report the case of a 24-year-old female patient who initially developed a neuroleptic malignant syndrome after haloperidol exposure and experienced 6 years later a serotonin syndrome after repeated fluoxetine exposure. The patient did not respond to symptomatic treatment and died in this latter episode. At necropsy, no gross or microscopic changes were seen with conventional histological stains, and immunohistochemical stains were negative. This is the first clinicopathologic case of a patient who experienced both neuroleptic malignant and serotonin syndromes. We speculate that this case argue in favor that both syndromes share some fundamental pathogenetic mechanisms. |
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Authors:
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Juan Carlos Gómez-Esteban; Joseba Barcena; Maribel Forcadas; Johanne Somme; Marta Agundez; Beatriz Tijero; Juan J Zarranz |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical neuropharmacology Volume: 32 ISSN: 1537-162X ISO Abbreviation: Clin Neuropharmacol Publication Date: 2009 Sep-Oct |
Date Detail:
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Created Date: 2009-10-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7607910 Medline TA: Clin Neuropharmacol Country: United States |
Other Details:
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Languages: eng Pagination: 299-300 Citation Subset: IM |
Affiliation:
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Department of Neuroscience, University of the Basque Country (UPV/EHU), Neurology Service, Hospital de Cruces, Baracaldo, Vizcaya, Spain. jgomeze@meditex.es |
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