| Neuroleptic malignant syndrome due to risperidone treatment in a child with Joubert syndrome. | |
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MedLine Citation:
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PMID: 19331262 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Joubert syndrome is a rare autosomal recessive disease characterized by hypotonia, ataxia, episodic hyperpnea, psychomotor retardation, abnormal ocular movements, cerebellar vermian hypoplasia, and molar tooth sign on magnetic resonance imaging. Neuroleptic malignant syndrome is an uncommon and potentially fatal idiosynchratic reaction of antipsychotic drugs, in which the clinical scenario encompass muscular rigidity, hyperthermia, autonomic dysfunction, altered consciousness, high creatinine phosphokinase levels, and leukocytosis. This report describes a case of neuroleptic malignant syndrome due to risperidone in a child with Joubert syndrome. |
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Authors:
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Sebahattin Vurucu; Ayhan Congologlu; Demet Altun; Bulent Unay; Ridvan Akin |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of the National Medical Association Volume: 101 ISSN: 0027-9684 ISO Abbreviation: J Natl Med Assoc Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-03-31 Completed Date: 2009-05-06 Revised Date: 2009-08-05 |
Medline Journal Info:
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Nlm Unique ID: 7503090 Medline TA: J Natl Med Assoc Country: United States |
Other Details:
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Languages: eng Pagination: 273-5 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, Gulhane Military Medical Academy, Ankara, Turkey. sebahattinvurucu@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple
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drug therapy*,
physiopathology Acetaminophen / therapeutic use Adolescent Analgesics, Non-Narcotic / therapeutic use Antipsychotic Agents / adverse effects* Biperiden / therapeutic use Cryotherapy Dopamine Antagonists / adverse effects* Humans Male Muscarinic Antagonists / therapeutic use Neuroleptic Malignant Syndrome* Risperidone / adverse effects* Serotonin Antagonists / adverse effects* |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Non-Narcotic; 0/Antipsychotic Agents; 0/Dopamine Antagonists; 0/Muscarinic Antagonists; 0/Serotonin Antagonists; 103-90-2/Acetaminophen; 106266-06-2/Risperidone; 514-65-8/Biperiden |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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