| Neuroleptic malignant syndrome and acute motor axonal neuropathy after Campylobacter jejuni infection. | |
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MedLine Citation:
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PMID: 19716463 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the case of a patient with Parkinson's disease who developed rapidly progressive weakness of the four limbs due to an acute motor axonal neuropathy (AMAN). This occurred days after a neuroleptic malignant syndrome (NMS). Serologic evidence of a preceding Campylobacter jejuni infection was detected and treatment with intravenous immunoglobulins proved effective. This case suggests that the rarely described neuropathies occurring with NMS may have a postinfectious immune basis and respond to immunomodulatory therapy. |
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Authors:
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Y A Rajabally; A Ramlackhansingh; M Fraser; R J Abbott |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-03-17 |
Journal Detail:
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Title: Neurophysiologie clinique = Clinical neurophysiology Volume: 39 ISSN: 1769-7131 ISO Abbreviation: - Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-08-31 Completed Date: 2009-11-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8804532 Medline TA: Neurophysiol Clin Country: France |
Other Details:
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Languages: eng Pagination: 135-8 Citation Subset: IM |
Affiliation:
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Department of Neurology, Neuromuscular Clinic, Leicester General Hospital, University Hospitals of Leicester, Leicester LE5 4PW, United Kingdom. yusuf.rajabally@uhl-tr.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antibodies, Bacterial
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blood,
immunology Antiparkinson Agents / adverse effects, therapeutic use Campylobacter Infections / complications*, diagnosis Campylobacter jejuni* Electromyography Fever / etiology G(M1) Ganglioside / immunology Guillain-Barre Syndrome / etiology*, therapy Humans Immunoglobulin G / blood, immunology Immunoglobulin M / blood, immunology Immunoglobulins, Intravenous / therapeutic use Lipopolysaccharides / immunology Male Middle Aged Molecular Mimicry Neural Conduction Neuroleptic Malignant Syndrome / etiology* Parkinson Disease / complications*, drug therapy Quadriplegia / etiology* Unconsciousness / etiology |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial; 0/Antiparkinson Agents; 0/Immunoglobulin G; 0/Immunoglobulin M; 0/Immunoglobulins, Intravenous; 0/Lipopolysaccharides; 37758-47-7/G(M1) Ganglioside |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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