| Neuroimmune pharmacology as a sub-discipline of medical neuroscience in the medical school curriculum. | |
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MedLine Citation:
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PMID: 21103946 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The emerging field of neuroimmune pharmacology (NIP) is the confluence of three distinct disciplines: neuroscience, immunology, and pharmacology (Gendelman and Ikezu 2008). NIP was born from the realization that inflammation within the central nervous system (CNS) plays a crucial role in many neurological pathologies and as such offers a rich array of novel pharmacological targets as potential therapeutics. As this field is likely to have a major impact in medical science, educating future physicians on this area will help increase awareness and may potentially inspire them to pursue careers in the field of NIP. However, a key challenge for medical educators, is how best to incorporate new material on emerging fields, such as NIP, into the medical school curriculum, specifically in the context of a medical neuroscience course. We propose the addition of two 50-min lectures plus an additional optional 2-h lab module to the standard first year medical neuroscience class curriculum. Lecture 1 will focus on how the CNS and the immune system inter-communicate with one another with emphasis on neuroanatomical features and chemical signal transduction between the two systems. Lecture 2 provides an introduction to inflammation in the CNS and provides a series of clinical correlates to describe how CNS inflammation contributes to the disease process. The lab module provides detailed visual examples of how CNS inflammation influences disease processes and provides two examples of how application of an immunomodulatory pharmacological agent can modify disease processes. |
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Authors:
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Robert W Freilich; Tsuneya Ikezu |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review Date: 2010-11-20 |
Journal Detail:
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Title: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology Volume: 6 ISSN: 1557-1904 ISO Abbreviation: J Neuroimmune Pharmacol Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-01-28 Completed Date: 2011-05-09 Revised Date: 2012-03-07 |
Medline Journal Info:
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Nlm Unique ID: 101256586 Medline TA: J Neuroimmune Pharmacol Country: United States |
Other Details:
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Languages: eng Pagination: 41-56 Citation Subset: IM |
Affiliation:
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Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, MA 02118, USA. robf999@bu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Allergy and Immunology
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education Education, Medical, Undergraduate / methods* Humans Neurosciences / education* Pharmacology / education |
| Grant Support | |
ID/Acronym/Agency:
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5T32GM008541/GM/NIGMS NIH HHS; R01 MH072539/MH/NIMH NIH HHS; R01 MH072539-05/MH/NIMH NIH HHS; R21 AG032600/AG/NIA NIH HHS; R21 AG032600-02/AG/NIA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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