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Neuroimaging and neuropathology of TBI.
MedLine Citation:
PMID:  21447905     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Neuroimaging at all stages of a traumatic brain injury (TBI) provides information about gross brain pathology. In this review, post-mortem TBI cases are matched to neuroimaging findings from TBI survivors to demonstrate the close correlation between observable pathology with in vivo neuroimaging to the underlying neuropathology. An emphasis of this review focuses on neuroimaging identification of trauma induced cortical and white matter degeneration along with hydrocephalus ex vacuo expansion of the ventricular system as the injured brain exhibits atrophic changes. The role of hippocampal atrophy and thalamic injury along with the vulnerability of the corpus callosum in TBI are also reviewed. The aim of this review is to provide pathological confirmation of observable neuroimaging abnormalities that relate directly to trauma-induced effects of the injury.
Authors:
Erin D Bigler; William L Maxwell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  NeuroRehabilitation     Volume:  28     ISSN:  1878-6448     ISO Abbreviation:  NeuroRehabilitation     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-03-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9113791     Medline TA:  NeuroRehabilitation     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  63-74     Citation Subset:  IM    
Affiliation:
Department of Psychology and Neuroscience Center, Brigham Young University, Provo, Utah, USA Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah, USA.
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