Document Detail


Neuroimaging in hepatic encephalopathy.
MedLine Citation:
PMID:  15765437     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hepatic encephalopathy (HE) is a poorly defined, complex neuropsychological disorder that often accompanies portal hypertension. Although the mechanisms underlining HE and the characterization of HE are still under investigation, the information derived from functional neuroimaging of patients with HE complemented by laboratory investigation and neuropsychological and neurophysiological studies have clarified much of the neuroanatomical defects. In this review, we have provided an outline of the understood mechanisms of HE and the associated findings on neuroimaging.
Authors:
Charmaine A Stewart; Martin Reivich; Michael R Lucey; Gregory J Gores
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association     Volume:  3     ISSN:  1542-3565     ISO Abbreviation:  Clin. Gastroenterol. Hepatol.     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-14     Completed Date:  2005-06-28     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  101160775     Medline TA:  Clin Gastroenterol Hepatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  197-207     Citation Subset:  IM    
Affiliation:
Division of Gastroenterology, Mayo Clinic, 200 First Street, Southwest, Rochester, Minnesota 55905, USA. stewart.charmaine@mayo.edu
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MeSH Terms
Descriptor/Qualifier:
Ammonia / adverse effects,  metabolism
Hepatic Encephalopathy / diagnosis*,  metabolism,  physiopathology
Humans
Magnetic Resonance Imaging*
Magnetic Resonance Spectroscopy*
Manganese / adverse effects,  metabolism
Positron-Emission Tomography*
Receptors, GABA-A / metabolism
Tomography, Emission-Computed, Single-Photon*
Grant Support
ID/Acronym/Agency:
K23DK60018-02/DK/NIDDK NIH HHS
Chemical
Reg. No./Substance:
0/Receptors, GABA-A; 7439-96-5/Manganese; 7664-41-7/Ammonia

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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