Document Detail


Neuroimaging biomarkers of epileptogenesis.
MedLine Citation:
PMID:  21303682     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Much progress has been made in the field studying the process of epileptogenesis via neuroimaging techniques. Conventional imaging methods include magnetic resonance imaging with morphometric analysis, magnetic resonance spectroscopy and positron emission tomography. Newer network-based methods such as diffusion tensor imaging and functional magnetic resonance imaging with resting functional connectivity are being developed and applied to clinical use. This review provides a brief summary of the major human and animal studies in both partial and generalized epilepsies that demonstrate the potential of these imaging modalities to serve as biomarkers of epileptogenesis.
Authors:
Asht Mangal Mishra; Harrison Bai; Alexandra Gribizis; Hal Blumenfeld
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review     Date:  2011-02-16
Journal Detail:
Title:  Neuroscience letters     Volume:  497     ISSN:  1872-7972     ISO Abbreviation:  Neurosci. Lett.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-06-06     Completed Date:  2012-03-02     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  7600130     Medline TA:  Neurosci Lett     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  194-204     Citation Subset:  IM    
Copyright Information:
Copyright © 2011. Published by Elsevier Ireland Ltd.
Affiliation:
Department of Neurology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA. asht.mishra@yale.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Biological Markers / metabolism*
Brain / metabolism*
Humans
Molecular Imaging / methods*
Nerve Tissue Proteins / metabolism*
Rats
Tissue Distribution
Grant Support
ID/Acronym/Agency:
P30 NS052519/NS/NINDS NIH HHS; P30 NS052519/NS/NINDS NIH HHS; R01 NS049307/NS/NINDS NIH HHS; R01 NS049307/NS/NINDS NIH HHS; R01 NS066974/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
0/Biological Markers; 0/Nerve Tissue Proteins
Comments/Corrections

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