Document Detail


Neuroimaging demonstration of evolving small vessel ischemic injury in cerebral amyloid angiopathy.
MedLine Citation:
PMID:  19850897     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND PURPOSE: Cerebral amyloid angiopathy is a small to medium vasculopathy most commonly associated with symptomatic intracerebral hemorrhage and microbleeds. Summary of Case- We present a patient with cerebral microbleeds and likely amyloid angiopathy with evolving ischemic lesions visualized on diffusion-weighted imaging. CONCLUSIONS: This case captures with serial MRI the evolving and dynamic nature of cerebral amyloid angiopathy and particularly illustrates the subclinical, yet progressive, ischemic aspects of this vasculopathic process.
Authors:
Ravi S Menon; Chelsea S Kidwell
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-10-22
Journal Detail:
Title:  Stroke; a journal of cerebral circulation     Volume:  40     ISSN:  1524-4628     ISO Abbreviation:  Stroke     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-25     Completed Date:  2010-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0235266     Medline TA:  Stroke     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e675-7     Citation Subset:  IM    
Affiliation:
Department of Neurology and Stroke Center, Georgetown University, Washington, DC 20007, USA. ravi.menon@gunet.georgetown.edu
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MeSH Terms
Descriptor/Qualifier:
Arterioles / pathology,  physiopathology
Brain / blood supply,  pathology,  physiopathology
Brain Ischemia / diagnosis*,  etiology*,  physiopathology
Causality
Cerebral Amyloid Angiopathy / complications*,  diagnosis*,  physiopathology
Cerebral Arteries / pathology*,  physiopathology
Cerebral Hemorrhage / diagnosis,  etiology,  physiopathology
Clinical Protocols
Diffusion Magnetic Resonance Imaging / methods
Disease Progression
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
Magnetic Resonance Angiography / methods
Male
Microcirculation / physiology
Middle Aged
Platelet Aggregation Inhibitors / therapeutic use
Risk Assessment
Risk Factors
Chemical
Reg. No./Substance:
0/Hydroxymethylglutaryl-CoA Reductase Inhibitors; 0/Platelet Aggregation Inhibitors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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