Document Detail


Neurohypophyseal germinoma traced from its earliest stage via magnetic resonance imaging: case report.
MedLine Citation:
PMID:  11738669     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: We report a case in which magnetic resonance imaging (MRI) documented the formation of a neurohypophyseal germinoma from its earliest stage. CASE DESCRIPTION: A 9-year-old girl presented with polyuria, polydipsia, and growth retardation. Urinary and endocrinological examination indicated diabetes insipidus (DI) and growth hormone deficiency. No clear evidence of a mass in the hypothalamo-pituitary area was apparent on the first MRI scan. Follow-up MRIs and endocrinological examinations revealed that a tumor, arising from the stalk and posterior lobe of the pituitary gland, formed a mass and caused anterior pituitary function to deteriorate. Histologic diagnosis was germinoma based on open biopsy. CONCLUSION: Radiologic findings in this case indicated the primary site of this intrasellar germinoma to be the hypothalamo-neurohypophyseal region, designating this a "neurohypophyseal germinoma."
Authors:
M Oishi; K Morii; H Okazaki; T Tamura; R Tanaka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Surgical neurology     Volume:  56     ISSN:  0090-3019     ISO Abbreviation:  Surg Neurol     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-12-13     Completed Date:  2002-01-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0367070     Medline TA:  Surg Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  236-41     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Brain Research Institute, Niigata University, 1-757 Asahimachi-doori, Niigata city, Niigata, 951-8585, Japan.
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MeSH Terms
Descriptor/Qualifier:
Child
Combined Modality Therapy
Disease Progression
Female
Germinoma / diagnosis*,  pathology,  surgery
Humans
Magnetic Resonance Imaging*
Neoplasm Staging
Pituitary Diseases / diagnosis*,  pathology,  surgery
Pituitary Neoplasms / diagnosis*,  pathology,  surgery

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