Document Detail

Neurohumoral mechanism of space motion sickness.
MedLine Citation:
PMID:  11542422     Owner:  NASA     Status:  MEDLINE    
This paper reviews existing hypotheses concerning the mechanisms of adaptation of the vestibular apparatus and related somatosensory systems to microgravity with reference to the flight data. Having in view theoretical concepts and experimental data accumulated in space flights, a conceptual model of the development of a funtional system responsible for the termination of vestibular dysfuntion and space motion sickness manifestations is presented. It is also shown that changes in the hormonal status during motion sickness induced by vestibular stimulation give evidence that endocrine regulation of certain functions can be involved in adaptive responses.
A I Grigoriev; A D Egorov; I A Nichiporuk
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta astronautica     Volume:  17     ISSN:  0094-5765     ISO Abbreviation:  Acta Astronaut     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1999-12-06     Completed Date:  1999-12-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9890631     Medline TA:  Acta Astronaut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  167-72     Citation Subset:  S    
Institute of Biomedical Problems, Moscow, USSR.
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MeSH Terms
Adaptation, Physiological / physiology*
Afferent Pathways
Disease Susceptibility
Efferent Pathways
Eye Movements
Hormones / blood,  metabolism*
Nervous System Physiological Phenomena
Space Flight*
Space Motion Sickness / etiology,  physiopathology*
Vestibule, Labyrinth / physiology*
Weightlessness / adverse effects*
Reg. No./Substance:

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