Document Detail

Neurohormonal factors in heart failure.
MedLine Citation:
PMID:  11072274     Owner:  NLM     Status:  MEDLINE    
Currently there are 4 to 5 million people with congestive heart failure in the United States. They consume greater than 7% of the total health care dollar of which a significant portion is directly related to hospitalization expenses alone. Most patients with chronic congestive heart failure can be managed efficiently outside the hospital setting by the proper use of nonpharmacologic therapies. Neurohormonal pathways have a significant impact on the progression of congestive heart failure. Medications, which include alpha-blockers, beta-blockers, digoxin, spironolactone, and diuretics, now can block, modify, or manage most of these neurohormonal effects, and therefore, have a stabilizing effect on the patient with congestive heart failure. Understanding the physiology and medications involved for optimal treatment of congestive heart failure is a must to ensure the quality of life that these patients deserve.
S D Mendzef
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Nursing clinics of North America     Volume:  35     ISSN:  0029-6465     ISO Abbreviation:  Nurs. Clin. North Am.     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2001-01-04     Completed Date:  2001-01-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0042033     Medline TA:  Nurs Clin North Am     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  841-53     Citation Subset:  AIM; IM; N    
North Medical Cardiovascular Group of Syracuse, Syracuse, New York, USA.
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MeSH Terms
Aldosterone / physiology
Cardiotonic Agents / therapeutic use*
Cytokines / physiology*
Heart Failure* / drug therapy,  economics
Renin-Angiotensin System / physiology
Sympathetic Nervous System / physiology*
Reg. No./Substance:
0/Cardiotonic Agents; 0/Cytokines; 52-39-1/Aldosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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