Document Detail

Neurogenic stunned myocardium associated with reversible posterior leukoencephalopathy syndrome.
MedLine Citation:
PMID:  18506639     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: Neurogenic stunned myocardium is characterized by transient left ventricular systolic dysfunction in the absence of significant obstructive coronary artery disease. Reversible posterior leukoencephalopathy syndrome (RPLS) is characterized by transient vasogenic subcortical edema without infarction. Both syndromes are hypothesized to result from sympathetic dysregulation. We report a case of neurogenic-stunned myocardium and RPLS occurring simultaneously in a patient. METHODS: Single case report. RESULTS: We present a 55-year-old woman with a history of hypertension and chronic back pain status post spinal cord stimulator who presented with severe headache, seizure, and confusion associated with acute hypertension. Magnetic resonance imaging (MRI) of the brain revealed bilateral patchy T(2) signal hyperintensity, consistent with RPLS. Transthoracic echocardiogram (TTE) showed regional-wall motion abnormalities in the apical regions, consistent with neurogenic-stunned myocardium. The patient's TTE and MRI abnormalities resolved on follow-up studies. CONCLUSION: Neurogenic-stunned myocardium and RPLS are two reversible clinical syndromes that are hypothesized to be a result of sympathetic dysregulation. Our case suggests that these two syndromes may occur together in the same patient.
Polo A Banuelos; Richard Temes; Vivien H Lee
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurocritical care     Volume:  9     ISSN:  1541-6933     ISO Abbreviation:  Neurocrit Care     Publication Date:  2008  
Date Detail:
Created Date:  2008-08-21     Completed Date:  2008-10-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101156086     Medline TA:  Neurocrit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  108-11     Citation Subset:  IM    
Rush University Medical Center, 1725 West Harrison Street, Chicago, IL 60612-3824, USA.
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MeSH Terms
Autonomic Nervous System Diseases / etiology*
Hypertension / complications
Intensive Care
Magnetic Resonance Imaging
Middle Aged
Myocardial Stunning / etiology*,  therapy
Posterior Leukoencephalopathy Syndrome / complications*,  pathology
Takotsubo Cardiomyopathy / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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