Document Detail

Neurogenic stunned myocardium associated with status epileptics and postictal catecholamine surge.
MedLine Citation:
PMID:  18277028     Owner:  NLM     Status:  MEDLINE    
A 75-year-old woman developed left ventricular apical ballooning, shortly after recovering from status epileptics. Plasma noradrenaline and adrenaline levels were 2.05 ng/ml and 0.48 ng/ml, respectively. Endomyocardial biopsy disclosed patchy areas of interstitial myocardial fibrosis, atrophy and vacuolization of cardiac myocytes, and some disappearance of myocyte nuclei. Follow-up echocardiography showed that the left ventricular apical ballooning was restored to normal within 25 days. These findings are compatible with neurogenic stunned myocardium. It is important to recognize that patients suffering from intractable seizures may harbor a risk of postictal catecholamine surge and catecholamine-induced myocardial dysfunction.
Masatoshi Shimizu; Ayako Kagawa; Takatsugu Takano; Hiroyuki Masai; Yoichi Miwa
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-02-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  47     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2008  
Date Detail:
Created Date:  2008-02-15     Completed Date:  2008-04-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  269-73     Citation Subset:  IM    
National Hospital Organization Kobe Medical Center-Cardiology, Kobe, Japan.
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MeSH Terms
Catecholamines / blood*
Myocardial Stunning / blood*,  etiology*
Status Epilepticus / complications*
Reg. No./Substance:

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