Document Detail

Neurogenic stunned myocardium after acute hydrocephalus.
MedLine Citation:
PMID:  20433252     Owner:  NLM     Status:  MEDLINE    
Neurogenic stunned myocardium (NSM) is a syndrome of cardiac stunning after a neurological insult. It is commonly observed after aneurysmal subarachnoid hemorrhage but is increasingly being reported after other neurological events. The underlying mechanism of NSM is believed to be a hypothalamic-mediated sympathetic surge causing weakened cardiac contractility and even direct cardiac myocyte damage. The authors report 2 cases of NSM in pediatric patients after acute hydrocephalus. Both patients experienced severe cardiac dysfunction in the acute phase but ultimately had a good neurological outcome and a full cardiac recovery. The identification, treatment, and outcome in 2 rare pediatric cases of NSM are discussed, and the history of the brain-cardiac connection is reviewed.
Jeremiah Johnson; John Ragheb; Ruchira Garg; William Patten; David I Sandberg; Sanjiv Bhatia
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurosurgery. Pediatrics     Volume:  5     ISSN:  1933-0715     ISO Abbreviation:  J Neurosurg Pediatr     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-03     Completed Date:  2010-05-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101463759     Medline TA:  J Neurosurg Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  428-33     Citation Subset:  IM    
Division of Pediatric Neurosurgery, University of Miami Miller School of Medicine, Lois Pope Life Center, 1095 NW 14th Terrace, Miami, Florida 33136, USA.
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MeSH Terms
Brain Stem Neoplasms / complications*,  diagnosis,  physiopathology,  surgery
Cerebellar Neoplasms / complications*,  diagnosis,  physiopathology,  surgery
Cerebral Aqueduct / physiopathology,  surgery
Child, Preschool
Constriction, Pathologic / complications,  diagnosis,  physiopathology,  surgery
Decompression, Surgical
Follow-Up Studies
Glioma / complications*,  diagnosis,  physiopathology,  surgery
Heart / innervation*
Hydrocephalus / complications*,  diagnosis,  physiopathology,  surgery
Hypothalamus / physiopathology*
Magnetic Resonance Imaging
Medulloblastoma / complications*,  diagnosis,  physiopathology,  surgery
Myocardial Stunning / diagnosis*,  physiopathology,  surgery
Sympathetic Nervous System / physiopathology*
Tectum Mesencephali / physiopathology*
Tomography, X-Ray Computed
Ventricular Dysfunction, Left / diagnosis,  physiopathology,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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