| Neurogenic pulmonary edema. | |
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MedLine Citation:
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PMID:Â 8316188 Â Â Â Owner:Â NLM Â Â Â Status:Â MEDLINE Â Â Â |
Abstract/OtherAbstract:
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The pathogenesis of nervous system-induced pulmonary edema remains incompletely understood. There are two major causes: elevated intravascular pressure and pulmonary capillary leak. Thus, both hemodynamic (cardiogenic) or nonhemodynamic (noncardiogenic) components exist. These components often occur together in settings such as pulmonary edema following epileptic convulsions or intracranial pressure elevation. The hemodynamic component is relatively brief and may unmask a "pure" noncardiogenic pulmonary edema such as that seen in experimental seizures (see Fig. 6). Whether the hemodynamic changes produce a pulmonary capillary leak through pressure-induced mechanical injury to the pulmonary capillaries or whether some direct nervous system control over pulmonary capillary permeability exists remains uncertain. The neuroeffector site for nervous system-induced pulmonary edema appears relatively well established in regions about the caudal medulla, where nuclei regulating systemic arterial pressure and afferent and efferent pathways to and from the lungs are located. |
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Authors:
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R P Simon |
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Publication Detail:
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Type: Journal Article; Review    |
Journal Detail:
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Title: Neurologic clinics    Volume: 11    ISSN: 0733-8619    ISO Abbreviation: Neurol Clin    Publication Date: 1993 May |
Date Detail:
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Created Date:Â 1993-07-27 Â Â Â Completed Date:Â 1993-07-27 Â Â Â Revised Date:Â 2005-11-16 Â Â Â |
Medline Journal Info:
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Nlm Unique ID: 8219232    Medline TA: Neurol Clin    Country: UNITED STATES    |
Other Details:
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Languages: eng    Pagination: 309-23    Citation Subset: IM    |
Affiliation:
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Department of Neurology, University of California, San Francisco. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Brain / drug effects, physiopathology, radiography Brain Diseases / complications, diagnosis Epilepsy Epinephrine / diagnostic use Female Humans Hypothalamus / drug effects, physiopathology Lung / physiology, physiopathology* Lung Diseases / diagnosis, etiology, physiopathology* Magnetic Resonance Imaging Male Pulmonary Edema / diagnosis, etiology, physiopathology* Rats |
| Chemical | |
Reg. No./Substance:
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51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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