Document Detail


Neurofibromatosis involving the small bowel associated with adenocarcinoma of the ileum with a neuroendocrine component.
MedLine Citation:
PMID:  1300607     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient with neurofibromatosis involving the small bowel who developed adenocarcinoma in an area of the ileum showing diffuse involvement of the disease is presented. Unlike the five cases with this association previously described, the present case shows a neuroendocrine component within the adenocarcinoma. The relation between neurofibromatosis of the bowel wall and adenocarcinoma may be explained by a decreased intestinal transit time in this patient. The presence of a carcinoid tumor in the ileum is not unusual in a patient with von Recklinghausen's disease, although the location of the carcinoid in the duodenum is described more frequently in these patients. The appearance of endocrine/neuroendocrine features within an adenocarcinoma already involved by diffuse neurofibromatosis is exceptional and may not be a chance event.
Authors:
D Benharroch; N Sion-Vardi; J Goldstein
Related Documents :
23233577 - Hemostatic defects in liver and renal dysfunction.
10235207 - Additional investigations fail to alter the diagnosis of irritable bowel syndrome in su...
12722937 - Cleaning up the river: a metaphor for functional digestive disorders.
14621277 - Etiology of portal hypertension may influence gastrointestinal transit.
16839897 - Enhanced retention of urea-nitrogen in patients on total parenteral nutrition for intes...
21615977 - Agraphia in korean patients with early onset alzheimer's disease.
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pathology, research and practice     Volume:  188     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-05-27     Completed Date:  1993-05-27     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  959-63     Citation Subset:  IM    
Affiliation:
Institute of Pathology, Soroka Medical Center, Beer-Sheva, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / pathology*
Aged
Carcinoid Tumor / pathology*
Humans
Ileal Neoplasms / pathology
Intestine, Small / pathology*
Male
Microscopy, Electron
Neurofibromatoses / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  What's new in the role of cytokines on osteoblast proliferation and differentiation?
Next Document:  Progressive multifocal leukoencephalopathy and gliomas in a HIV-negative patient.