Document Detail


Neuroendocrinology of coping styles: towards understanding the biology of individual variation.
MedLine Citation:
PMID:  20382177     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Individual variation in behavior and physiology is a widespread and ecologically functional phenomenon in nature in virtually all vertebrate species. Due to domestication of laboratory animals, studies may suffer from a strong selection bias. This paper summarizes behavioral, neuroendocrine and neurobiological studies using the natural individual variation in rats and mice. Individual behavioral characteristics appear to be consistent over time and across situations. The individual variation has at least two dimensions in which the quality of the response to a challenging condition (coping style) is independent from the quantity of that response (stress reactivity). The neurobiology reveals important differences in the homeostatic control of the serotonergic neuron and the neuropeptides vasopressin and oxytocin in relation to coping style. It is argued that a careful exploitation of the broad natural and biologically functional individual variation in behavior and physiology may help in developing better animal models for understanding individual disease vulnerability.
Authors:
J M Koolhaas; S F de Boer; C M Coppens; B Buwalda
Related Documents :
20040917 - Model or meal? farm animal populations as models for infectious diseases of humans.
12404097 - Marfan syndrome in the third millennium.
21039807 - Vertical dimensions of suspended horses.
17014267 - Modeling the effects of the nmda receptor antagonist mk-801 on timing in rats.
21042977 - Assessment of nanomaterials cytotoxicity and internalization.
15376867 - A combined fuzzy-neural network model for non-linear prediction of 3-d rendering worklo...
Publication Detail:
Type:  Journal Article; Review     Date:  2010-04-09
Journal Detail:
Title:  Frontiers in neuroendocrinology     Volume:  31     ISSN:  1095-6808     ISO Abbreviation:  Front Neuroendocrinol     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-26     Completed Date:  2010-11-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7513292     Medline TA:  Front Neuroendocrinol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  307-21     Citation Subset:  IM    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Dept. of Behavioural Physiology, University Groningen, 9750 AA Haren, The Netherlands. j.m.koolhaas@rug.nl
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adaptation, Psychological / physiology*
Animals
Humans
Individuality*
Mice
Models, Biological
Neurobiology
Neuroendocrinology
Neurosecretory Systems / physiology*
Rats

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Rare but precious: microsaccades are highly informative about attentional allocation.
Next Document:  Prevalence and Predictors of Recommendations to Lose Weight in Overweight and Obese Older Adults in ...