Document Detail


Neuroendocrine small cell carcinoma of the uterine cervix showing polypoid growth and complicated by pregnancy.
MedLine Citation:
PMID:  11277662     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Neuroendocrine small cell carcinoma of the uterine cervix is an aggressive disease, and it rarely is complicated by pregnancy. CASE: A polypoid tumor was found in the uterine cervix in a 27-year-old Japanese woman at 27 weeks of gestation. No polyp had been detected at 14 weeks of gestation. The polyp was excised and diagnosed as neuroendocrine small cell carcinoma by histological examination, including Grimelius, neuron-specific enolase, and chromogranin staining. A healthy infant was born by cesarean section at 29 weeks of gestation: this was followed by radical hysterectomy with pelvic lymphadenectomy. After surgery, four cycles of combination chemotherapy with cisplatin and etoposide were administered, and the patient is disease-free as of 13 months after surgery. CONCLUSION: When a polypoid lesion is found, especially when it demonstrates rapid growth, it may be necessary to excise and histologically examine the polyp even during pregnancy.
Authors:
M Ohwada; M Suzuki; M Hironaka; T Irie; I Sato
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Gynecologic oncology     Volume:  81     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-03-30     Completed Date:  2001-04-26     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  117-9     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Academic Press.
Affiliation:
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan. mohwada@jichi.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Carcinoma, Neuroendocrine / drug therapy,  pathology*,  surgery
Carcinoma, Small Cell / drug therapy,  pathology*,  surgery
Cell Division / physiology
Female
Humans
Polyps / drug therapy,  pathology,  surgery
Pregnancy
Pregnancy Complications, Neoplastic / pathology*
Uterine Cervical Neoplasms / drug therapy,  pathology*,  surgery

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