Document Detail


Neuroendocrine carcinoma (carcinoid) of the thymus associated with Cushing's syndrome.
MedLine Citation:
PMID:  11845907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Neuroendocrine carcinoma (carcinoid) of the thymus associated with Cushing's syndrome is a rare disease. Recent evidence suggests that these tumors form part of a continuous spectrum ranging from well-differentiated carcinomas to small cell carcinomas. We report two new cases and review the 23 cases reported in the literature since 1972. The different diagnostic modalities are discussed, and an algorithm for the diagnosis of ectopic secretion of adrenocorticotropin (ACTH) is presented. In the future, the advent of radiologic and nuclear imaging as well as more accurate workup should help to diagnose these tumors at an earlier stage and improve the long-term outcome.
Authors:
Marc de Perrot; Anastase Spiliopoulos; Stefan Fischer; Martin Totsch; Shaf Keshavjee
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  73     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-02-15     Completed Date:  2002-03-06     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  675-81     Citation Subset:  AIM; IM    
Affiliation:
Division of Thoracic Surgery, Toronto General Hospital, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
ACTH Syndrome, Ectopic / diagnosis,  pathology,  surgery*
Adult
Algorithms
Carcinoid Tumor / diagnosis,  pathology,  surgery*
Cushing Syndrome / diagnosis,  pathology,  surgery*
Diagnosis, Differential
Female
Humans
Thymectomy
Thymus Gland / pathology
Thymus Neoplasms / diagnosis,  pathology,  surgery*
Comments/Corrections
Comment In:
Ann Thorac Surg. 2003 Feb;75(2):633   [PMID:  12607697 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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