| Neurodevelopmental pathways to aggression: a model to understand and target treatment in youth. | |
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MedLine Citation:
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PMID: 16963580 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The authors describe a neurodevelopmentally relevant, clinically derived model for understanding and treating aggressive behavior in youth. Based on case experience and literature review, the authors divide aggressive behavior into five symptomatic domains with respective neurobiological/neurodevelopmental underpinnings. These five symptom domains (impulsivity, affective instability, anxious/hyperarousal, cognitive disorganization, and predatory aggression) emerge as logical and clinically useful targets for treatment. The authors aim to establish a relationship between these symptom domains and brain structure and function that offers a clinically relevant approach to the complexities of understanding aggression and its treatment. |
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Authors:
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Steven G Sugden; Shawn J Kile; Robert L Hendren |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The Journal of neuropsychiatry and clinical neurosciences Volume: 18 ISSN: 0895-0172 ISO Abbreviation: J Neuropsychiatry Clin Neurosci Publication Date: 2006 |
Date Detail:
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Created Date: 2006-09-11 Completed Date: 2006-10-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8911344 Medline TA: J Neuropsychiatry Clin Neurosci Country: United States |
Other Details:
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Languages: eng Pagination: 302-17 Citation Subset: IM |
Affiliation:
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Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adrenergic Agents / therapeutic use Aggression / physiology*, psychology Anti-Anxiety Agents / therapeutic use Antidepressive Agents / therapeutic use Antipsychotic Agents / therapeutic use Anxiety / physiopathology Arousal / physiology Central Nervous System Stimulants / therapeutic use Child Cognition / physiology Female Humans Hypothalamo-Hypophyseal System / physiopathology Impulsive Behavior / physiopathology, psychology, therapy Male Mood Disorders / physiopathology, psychology, therapy Nervous System / growth & development*, physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic Agents; 0/Anti-Anxiety Agents; 0/Antidepressive Agents; 0/Antipsychotic Agents; 0/Central Nervous System Stimulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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